Botox, Dysport, or Xeomin? A Refresher on What You Actually Need to Know

When it comes to smoothing out fine lines and wrinkles, all neurotoxins are not created equal — and no, you don’t have to pretend you understand the difference between them at your next med spa appointment. We got you. 

First Things First: What Are These? 

Botox, Dysport, and Xeomin are all FDA-approved neurotoxins made from botulinum toxin type A. They work by temporarily relaxing the muscle activity that causes wrinkles — think frown lines, forehead creases, and crow’s feet. So, while they’re all in the same family, they’ve got different personalities. 

Botox – The OG 

Botox is basically the Kris Jenner of neurotoxins. It’s been around the longest, it’s well-known, and it knows how to work a camera. 

    •    Best for: Fine lines, moderate-to-severe wrinkles, and when you want predictable, long-lasting results. 

    •    Kicks in: 3–7 days 

    •    Lasts: About 3–4 months 

    •    Bonus: Tried-and-true. If you’re new to injectables, Botox is a solid starter. 

Dysport – The Fast-Acting Baddie 

Dysport is like the younger, slightly edgier cousin who shows up early and overstays her welcome (in a good way). 

    •    Best for: Forehead lines or areas with broader muscle movement (hi, strong elevens). 

    •    Kicks in: 1–3 days — lightning fast! 

    •    Lasts: Around 3–4 months (some people swear it’s longer!) 

    •    Bonus: Great if you want to see results FAST, especially for last-minute events or hot dates. 

Xeomin – The Clean Girl Aesthetic 

Xeomin is stripped down — no additives, no frills, just pure botulinum toxin. It’s basically the minimalist of the bunch. 

    •    Best for: People who have built up resistance to other toxins or want fewer ingredients. 

    •    Kicks in: 3–4 days 

    •    Lasts: About 3–4 months 

    •    Bonus: Called the “naked injectable” because it contains fewer proteins, which may reduce the risk of building up resistance over time. 

So… Which One’s Best? 

There’s no one-size-fits-all answer (sorry, we hate that too). It depends on your goals, budget, how fast you want results, and what areas you’re treating. The good news? Our injectors at Upkeep are literal artists and will help you pick the one that’s right for your face and lifestyle. 

Still Not Sure? 

Book a free consult with one of our providers — we’ll talk through your goals and give you a plan that makes sense for your face, your muscle movement, and your budget. Because yes, you deserve to look like you slept 8 hours, even if you’ve been spiraling on TikTok till 2am.